YouTube: https://youtube.com/watch?v=zEnWZcG3Nzk
Previous: Why Do Some Drugs Make Your Pupils Wider?
Next: 3 (Actually Safe) Ways to Fight Climate Change

Categories

Statistics

View count:120,749
Likes:3,839
Dislikes:70
Comments:395
Duration:30:37
Uploaded:2018-03-28
Last sync:2019-12-05 19:00
Andrea and Don Stierle talk with Hank about their work analyzing various microorganisms in the Berkeley Pit and how they discovered a new type of antibiotic. Then Jessi joins in to show off Blueberry, the northern blue-tongued skink.

Hosted by: Hank Green

Head to https://scishowfinds.com/ for hand selected artifacts of the universe!
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Dooblydoo thanks go to the following Patreon supporters: Lazarus G, Kelly Landrum Jones, Sam Lutfi, Kevin Knupp, Nicholas Smith, D.A. Noe, alexander wadsworth, سلطان الخليفي, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Charles Southerland, Bader AlGhamdi, James Harshaw, Patrick Merrithew, Patrick D. Ashmore, Candy, Tim Curwick, charles george, Saul, Mark Terrio-Cameron, Viraansh Bhanushali, Kevin Bealer, Philippe von Bergen, Chris Peters, Justin Lentz
----------
Looking for SciShow elsewhere on the internet?
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Tumblr: http://scishow.tumblr.com
Instagram: http://instagram.com/thescishow

 (00:00) to (02:00)


(Intro)

Hello! And welcome to Sci Show Talk Show the (show) where we talk to intresting people about intresting things and today we are talking to Andrea and Don Stierle reasurch scientists at the University of Montana, who have done a lot of amazing things in your long carrear as scientists.
H: So you guys are married. But you have also been doing reasurch together for thirty plus years?
A: Absolutly
H: And have been looking at the Berkeley Pit for intresting organisms that may live there that may be useful to humans.
A: Absolutly!
H: So, talk a little bit about, like, uh, what each of you do and... So you have taught, but you no longer teach; you are just reasurchers now?
A: Correct. We are strictly reasurch professors at UM.
H: Okay
A: So I am more of the biology end of things, so wheather we are looking at microbes in the Berkley Pitt or microbes in the bark of a yew tree, the first step, of course, is to isolate these microorganisms, and we pick fungi and sometimes bacteria because they are great chemists. They do beautiful chemistry, and they do chemistry with a reason. They live in an ecosystem that they have to interact with, so they may be fighting off other fungi or bacteria, so they have to make antibiotics like penicillin. They may also have to react to low PH, acidic conditions, or high metals, and so they produce small molecules to defend themselves. Humans can isolate those chemicals and use them for our own purpaces. So I isolate these guys, establish them in pure culture, grow them in fermentation broths.
H: How do you take one from a bucket of Berkley Pitt water?
A: Streak and streak and streak and streak.
H: So, like, this one, take it out and put it here, and take that out and put it here. (Motioning moving it container to container)
A: Exactly! And you slowly come up with pure cultures.
H: And you can tell the difference by looking at that?
A: Absolutly! Their morphology is different and you can grow them in their different broths so whether you feed them sucrose or glucose or lactose you change their chemistry.

 (02:00) to (04:00)


 (04:00) to (06:00)


 (06:00) to (08:00)


 (08:00) to (10:00)


 (10:00) to (12:00)


 (12:00) to (14:00)


 (14:00) to (16:00)


 (16:00) to (18:00)


 (18:00) to (20:00)


 (20:00) to (22:00)


 (22:00) to (24:00)


 (24:00) to (26:00)


 (26:00) to (28:00)


 (28:00) to (30:00)


 (30:00) to (30:37)