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How We Could Beat Childhood Peanut Allergies | SciShow News
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Likes: | 9,375 |
Comments: | 766 |
Duration: | 06:33 |
Uploaded: | 2022-01-28 |
Last sync: | 2024-12-03 19:45 |
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Citation formatting is not guaranteed to be accurate. | |
MLA Full: | "How We Could Beat Childhood Peanut Allergies | SciShow News." YouTube, uploaded by SciShow, 28 January 2022, www.youtube.com/watch?v=BmkiwfL_o7Q. |
MLA Inline: | (SciShow, 2022) |
APA Full: | SciShow. (2022, January 28). How We Could Beat Childhood Peanut Allergies | SciShow News [Video]. YouTube. https://youtube.com/watch?v=BmkiwfL_o7Q |
APA Inline: | (SciShow, 2022) |
Chicago Full: |
SciShow, "How We Could Beat Childhood Peanut Allergies | SciShow News.", January 28, 2022, YouTube, 06:33, https://youtube.com/watch?v=BmkiwfL_o7Q. |
Go to https://thld.co/munkpack_scishow0122 and use code SCISHOW to get 20% off your first purchase! Thanks to Munk Pack for sponsoring today’s video!
More and more kids are avoiding peanut butter due to life threatening allergies, but we could make it so that no kid goes without a PBJ.
Hosted by: Hank Green
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Dr. Melvin Sanicas, Sam Lutfi, Bryan Cloer, Christoph Schwanke, Kevin Bealer, Jacob, Nazara, Ash, Jason A Saslow, Matt Curls, Eric Jensen, GrowingViolet, Jeffrey Mckishen, Christopher R Boucher, Alex Hackman, Piya Shedden, charles george, Tom Mosner, Jeremy Mysliwiec, Adam Brainard, Chris Peters, Silas Emrys, Alisa Sherbow
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Looking for SciShow elsewhere on the internet?
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Sources:
https://www.eurekalert.org/news-releases/940772
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02390-4/fulltext
https://www.nature.com/articles/d41586-022-00119-1
https://www.cambridge.org/core/journals/antiquity/article/party-like-a-sumerian-reinterpreting-the-sceptres-from-the-maikop-kurgan/EFEEFA5BD92653748F5A0F04CD133184
IMAGES
https://www.istockphoto.com/photo/crunchy-and-smooth-peanut-butter-on-bread-gm669160414-122259303
https://www.istockphoto.com/photo/healthcare-and-medical-concept-female-scratching-the-itch-on-her-hand-cause-of-gm1127255820-297035710
https://www.istockphoto.com/photo/young-woman-with-asthma-attack-or-respiratory-problem-gm680793694-125020811
https://www.istockphoto.com/photo/fresh-apple-sauce-gm175519926-20810153
https://www.istockphoto.com/photo/peanut-butter-gm476278344-66505393
https://www.istockphoto.com/photo/childhood-allergies-gm875554900-244423342
https://www.istockphoto.com/photo/peanut-butter-and-jelly-gm486199796-72424381
https://www.cambridge.org/core/journals/antiquity/article/party-like-a-sumerian-reinterpreting-the-sceptres-from-the-maikop-kurgan/EFEEFA5BD92653748F5A0F04CD133184#figures
https://commons.wikimedia.org/wiki/File:Kurgan-2_Maykop.JPG
https://commons.wikimedia.org/wiki/File:%D0%9A%D1%80%D0%BE%D0%BC%D0%BB%D0%B5%D1%85_%D0%BA%D1%83%D1%80%D0%B3%D0%B0%D0%BD%D0%B0_04.JPG
https://www.istockphoto.com/photo/harvesting-ripe-barley-gm1165760211-320883079
https://commons.wikimedia.org/wiki/File:Cylinder_seal_and_modern_impression-_banquet_scene_with_seated_figures_drinking_a_liquid_through_straws_MET_ss56_157_1.jpg
More and more kids are avoiding peanut butter due to life threatening allergies, but we could make it so that no kid goes without a PBJ.
Hosted by: Hank Green
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Dr. Melvin Sanicas, Sam Lutfi, Bryan Cloer, Christoph Schwanke, Kevin Bealer, Jacob, Nazara, Ash, Jason A Saslow, Matt Curls, Eric Jensen, GrowingViolet, Jeffrey Mckishen, Christopher R Boucher, Alex Hackman, Piya Shedden, charles george, Tom Mosner, Jeremy Mysliwiec, Adam Brainard, Chris Peters, Silas Emrys, Alisa Sherbow
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: http://www.scishowtangents.org
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
----------
Sources:
https://www.eurekalert.org/news-releases/940772
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02390-4/fulltext
https://www.nature.com/articles/d41586-022-00119-1
https://www.cambridge.org/core/journals/antiquity/article/party-like-a-sumerian-reinterpreting-the-sceptres-from-the-maikop-kurgan/EFEEFA5BD92653748F5A0F04CD133184
IMAGES
https://www.istockphoto.com/photo/crunchy-and-smooth-peanut-butter-on-bread-gm669160414-122259303
https://www.istockphoto.com/photo/healthcare-and-medical-concept-female-scratching-the-itch-on-her-hand-cause-of-gm1127255820-297035710
https://www.istockphoto.com/photo/young-woman-with-asthma-attack-or-respiratory-problem-gm680793694-125020811
https://www.istockphoto.com/photo/fresh-apple-sauce-gm175519926-20810153
https://www.istockphoto.com/photo/peanut-butter-gm476278344-66505393
https://www.istockphoto.com/photo/childhood-allergies-gm875554900-244423342
https://www.istockphoto.com/photo/peanut-butter-and-jelly-gm486199796-72424381
https://www.cambridge.org/core/journals/antiquity/article/party-like-a-sumerian-reinterpreting-the-sceptres-from-the-maikop-kurgan/EFEEFA5BD92653748F5A0F04CD133184#figures
https://commons.wikimedia.org/wiki/File:Kurgan-2_Maykop.JPG
https://commons.wikimedia.org/wiki/File:%D0%9A%D1%80%D0%BE%D0%BC%D0%BB%D0%B5%D1%85_%D0%BA%D1%83%D1%80%D0%B3%D0%B0%D0%BD%D0%B0_04.JPG
https://www.istockphoto.com/photo/harvesting-ripe-barley-gm1165760211-320883079
https://commons.wikimedia.org/wiki/File:Cylinder_seal_and_modern_impression-_banquet_scene_with_seated_figures_drinking_a_liquid_through_straws_MET_ss56_157_1.jpg
Thank you to Munk Pack for sponsoring today’s episode!
Munk Pack offers low-sugar bars which are plant-based, gluten free, and keto friendly. If you click the link in the description, you’ll receive 20% off your first purchase of any Munk Pack product! [ ♫ INTRO ♫ ] While some of us debate whether smooth or chunky is the superior peanut butter, about two percent of young people don’t really care, because either kind terrorizes their bodies.
Over the past 2 decades, food allergies have been on the rise, at least in the US. And the worst reactions can be fatal. So scientists are hunting for ways to stem the proverbial tide.
Last week in The Lancet, a clinical trial reported that toddlers with peanut allergies could be helped by feeding them… ground up peanuts. Allergic reactions happen when our body’s immune system misidentifies a benign substance as dangerous. Just like with actual disease-causing agents, it creates antibodies that react to subsequent “invasions”.
Side effects can range from a runny nose, to an itchy rash, all the way to anaphylaxis – where your body responds by releasing a flood of chemicals… which sends your body into shock, and your airway narrows up so much you might not be able to breathe. Thanks a lot, immune system. You took a fluffy bunny rabbit and turned it into the fluffy bunny rabbit from Monty Python and the Holy Grail.
But the allergens themselves aren’t actually dangerous. The real threat is your body’s overreaction. So it’s thought that exposure to small amounts may help desensitize the immune system while it’s still developing.
In fact, previous studies have demonstrated that this immunotherapy could be safely given to very young children, and might actually have a positive effect. So in this clinical trial, researchers recruited 146 kids aged 1 to 3 years old who had allergic reactions after eating an equivalent of 1 and a half peanuts. Or fewer.
Two-thirds were given peanut flour mixed into applesauce or pudding, and the rest given oat flour as a control. And they ate this stuff daily for two and a half years. They worked their way up to eating the equivalent of 16 peanuts, or 1.5 tablespoons of peanut butter, before quitting cold turkey.
Six months later, the kids received another 16-peanut dose to see if their immune system would react. Those that didn’t actually got to try some real peanut butter just to confirm. Right when they stopped the treatments, 71% of the kids had become desensitized to peanuts, but after the 6-month waiting period, that dropped to 21%.~ Still that’s a better result than the control group, which had only 1 kid become desensitized.
Though a good handful of participants had dropped out of each group by this point, which could affect the results. The immunotherapy also seemed to work better on the youngest kids, and the ones who had fewer peanut-targeting antibodies. However, the math was skewed by the fact that there were a lot fewer kids under two.
So that’s not a definitive result. It’s also worth noting that most of the kids did suffer some level of allergic reaction, and twenty-one of them got a dose of epinephrine to counteract the physical effects of anaphylaxis. So this isn’t something that should be done without a doctor’s okay.
Still, these results are promising, and hint at a future where more of us might get to enjoy a classic PB&J. But for the grownups, there’s a different peanut pairing available. Archeology is hard.
You excavate some artifacts, and then have to work out what exactly they are on your own, because anyone who could help is long gone.~ In 1897, one team excavated a burial mound in what’s now southwest Russia, called the Maikop kurgan. And one set of artifacts they uncovered was these thin, meter-long metal tubes. The tomb was dated to be about 5,500 years old, placing these tubes solidly in the part of history known as the Bronze Age.
They were all buried with one individual, along with some of the finer things in life, like semi-precious stone beads.~ And the tubes weren’t made of bronze, but silver and gold. Four were also decorated with detachable bull figurines which could slide up and down the tube without falling off the wider end, since they were slightly tapered. On the other end, all of them had these elaborately crafted, perforated tips.
The leader of the original investigation hypothesized they could be scepters of some kind. The holes indicated they could be decorated with cloth ribbons or some horse hair. About two decades later, another guy proposed they could be poles for some sort of canopy used to cover a dead body during a funeral procession.
By the 1980s, a third researcher noted they also found arrowheads in the burial mound, so he thought they could represent a bunch of arrow shafts, and were used by Zoroastrian priests in some religious ritual.~ But none of these hypotheses really addressed the fact that these were hollow tubes, not solid poles. All of these researchers oriented the tubes so the perforated tips were at the top. But the tubes were buried with the tips pointing down, toward the skeleton’s feet.
So in a study published last week in the journal Antiquity, another team asked, what if you turned them around? When analyzing the tips, they found barley starch residue. Since barley has been used to make beer as far back as 11,000 BCE, they propose these tubes weren’t scepters.
Or scaffolding. They were straws. The perforated tips might have served as strainers to keep these Bronze Age drinkers from slurping up any barley clumps or other impurities.
If that turns out to be true, and we may never know for sure, this would be the oldest use of straws ever documented. The team’s hypothesis is backed up by other archeological evidence. Seals found in the Middle East, dating back to either the 4th or 5th millennium BCE, depict drinking through a straw.
Actual straws from younger sites are of a similar size, and also have these strainer ends. And Mesopotamian art from the third millennium BCE shows a bunch of people drinking from the same communal jar. Like an antique beer milkshake.~ And there was a large jar found in the tomb with these tubes, which could hold about 32 liters.
Throw in some peanuts, and you’ve got yourselves a grand old time. And if you’re lucky enough not to be allergic to peanuts, you might just be interested in today’s sponsor, Munk Pack. Their Keto Granola Bars and Nut & Seed Bars contain 1 gram of sugar or less, 2 to 3 grams of net carbs and each bar contains 150 calories or less.
They’re made from simple ingredients – like peanuts – and come in flavors like Peanut Butter Dark Chocolate, as well as plenty of non-peanut flavors. You can get 20% off your first purchase of any Munk Pack product by visiting Munkpack.com and entering code scishow at checkout, or click the link in the description down below. Your purchase is backed with a 100% happiness guarantee — so if you don’t like it for any reason, Munk Pack will exchange the product or refund your money, whichever you prefer. [ ♫ OUTRO ♫ ]
Munk Pack offers low-sugar bars which are plant-based, gluten free, and keto friendly. If you click the link in the description, you’ll receive 20% off your first purchase of any Munk Pack product! [ ♫ INTRO ♫ ] While some of us debate whether smooth or chunky is the superior peanut butter, about two percent of young people don’t really care, because either kind terrorizes their bodies.
Over the past 2 decades, food allergies have been on the rise, at least in the US. And the worst reactions can be fatal. So scientists are hunting for ways to stem the proverbial tide.
Last week in The Lancet, a clinical trial reported that toddlers with peanut allergies could be helped by feeding them… ground up peanuts. Allergic reactions happen when our body’s immune system misidentifies a benign substance as dangerous. Just like with actual disease-causing agents, it creates antibodies that react to subsequent “invasions”.
Side effects can range from a runny nose, to an itchy rash, all the way to anaphylaxis – where your body responds by releasing a flood of chemicals… which sends your body into shock, and your airway narrows up so much you might not be able to breathe. Thanks a lot, immune system. You took a fluffy bunny rabbit and turned it into the fluffy bunny rabbit from Monty Python and the Holy Grail.
But the allergens themselves aren’t actually dangerous. The real threat is your body’s overreaction. So it’s thought that exposure to small amounts may help desensitize the immune system while it’s still developing.
In fact, previous studies have demonstrated that this immunotherapy could be safely given to very young children, and might actually have a positive effect. So in this clinical trial, researchers recruited 146 kids aged 1 to 3 years old who had allergic reactions after eating an equivalent of 1 and a half peanuts. Or fewer.
Two-thirds were given peanut flour mixed into applesauce or pudding, and the rest given oat flour as a control. And they ate this stuff daily for two and a half years. They worked their way up to eating the equivalent of 16 peanuts, or 1.5 tablespoons of peanut butter, before quitting cold turkey.
Six months later, the kids received another 16-peanut dose to see if their immune system would react. Those that didn’t actually got to try some real peanut butter just to confirm. Right when they stopped the treatments, 71% of the kids had become desensitized to peanuts, but after the 6-month waiting period, that dropped to 21%.~ Still that’s a better result than the control group, which had only 1 kid become desensitized.
Though a good handful of participants had dropped out of each group by this point, which could affect the results. The immunotherapy also seemed to work better on the youngest kids, and the ones who had fewer peanut-targeting antibodies. However, the math was skewed by the fact that there were a lot fewer kids under two.
So that’s not a definitive result. It’s also worth noting that most of the kids did suffer some level of allergic reaction, and twenty-one of them got a dose of epinephrine to counteract the physical effects of anaphylaxis. So this isn’t something that should be done without a doctor’s okay.
Still, these results are promising, and hint at a future where more of us might get to enjoy a classic PB&J. But for the grownups, there’s a different peanut pairing available. Archeology is hard.
You excavate some artifacts, and then have to work out what exactly they are on your own, because anyone who could help is long gone.~ In 1897, one team excavated a burial mound in what’s now southwest Russia, called the Maikop kurgan. And one set of artifacts they uncovered was these thin, meter-long metal tubes. The tomb was dated to be about 5,500 years old, placing these tubes solidly in the part of history known as the Bronze Age.
They were all buried with one individual, along with some of the finer things in life, like semi-precious stone beads.~ And the tubes weren’t made of bronze, but silver and gold. Four were also decorated with detachable bull figurines which could slide up and down the tube without falling off the wider end, since they were slightly tapered. On the other end, all of them had these elaborately crafted, perforated tips.
The leader of the original investigation hypothesized they could be scepters of some kind. The holes indicated they could be decorated with cloth ribbons or some horse hair. About two decades later, another guy proposed they could be poles for some sort of canopy used to cover a dead body during a funeral procession.
By the 1980s, a third researcher noted they also found arrowheads in the burial mound, so he thought they could represent a bunch of arrow shafts, and were used by Zoroastrian priests in some religious ritual.~ But none of these hypotheses really addressed the fact that these were hollow tubes, not solid poles. All of these researchers oriented the tubes so the perforated tips were at the top. But the tubes were buried with the tips pointing down, toward the skeleton’s feet.
So in a study published last week in the journal Antiquity, another team asked, what if you turned them around? When analyzing the tips, they found barley starch residue. Since barley has been used to make beer as far back as 11,000 BCE, they propose these tubes weren’t scepters.
Or scaffolding. They were straws. The perforated tips might have served as strainers to keep these Bronze Age drinkers from slurping up any barley clumps or other impurities.
If that turns out to be true, and we may never know for sure, this would be the oldest use of straws ever documented. The team’s hypothesis is backed up by other archeological evidence. Seals found in the Middle East, dating back to either the 4th or 5th millennium BCE, depict drinking through a straw.
Actual straws from younger sites are of a similar size, and also have these strainer ends. And Mesopotamian art from the third millennium BCE shows a bunch of people drinking from the same communal jar. Like an antique beer milkshake.~ And there was a large jar found in the tomb with these tubes, which could hold about 32 liters.
Throw in some peanuts, and you’ve got yourselves a grand old time. And if you’re lucky enough not to be allergic to peanuts, you might just be interested in today’s sponsor, Munk Pack. Their Keto Granola Bars and Nut & Seed Bars contain 1 gram of sugar or less, 2 to 3 grams of net carbs and each bar contains 150 calories or less.
They’re made from simple ingredients – like peanuts – and come in flavors like Peanut Butter Dark Chocolate, as well as plenty of non-peanut flavors. You can get 20% off your first purchase of any Munk Pack product by visiting Munkpack.com and entering code scishow at checkout, or click the link in the description down below. Your purchase is backed with a 100% happiness guarantee — so if you don’t like it for any reason, Munk Pack will exchange the product or refund your money, whichever you prefer. [ ♫ OUTRO ♫ ]