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View count:15,822
Likes:1,517
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Duration:40:41
Uploaded:2023-10-01
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MLA Full: "Saturday Night PIZZAMAS PARTY." YouTube, uploaded by vlogbrothers, 1 October 2023, www.youtube.com/watch?v=2KBfM7cUJos.
MLA Inline: (vlogbrothers, 2023)
APA Full: vlogbrothers. (2023, October 1). Saturday Night PIZZAMAS PARTY [Video]. YouTube. https://youtube.com/watch?v=2KBfM7cUJos
APA Inline: (vlogbrothers, 2023)
Chicago Full: vlogbrothers, "Saturday Night PIZZAMAS PARTY.", October 1, 2023, YouTube, 40:41,
https://youtube.com/watch?v=2KBfM7cUJos.
http://pizzamas.com

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Hello.

Welcome. There's nobody here, so welcome to nobody.

Welcome to our Saturday night celebration party. It's a party y'all, we're celebrating. Hi Helen.

Helen's the first person here. Ooh, that champagne is not very good, but then once I get used to it, it'll get better. That's the thing with champagne.

So I've got a bottle of Chandon. It was a ... I'm allowed -- it was on the bottom row of our little wine fridge, and anything on the bottom row is not so good that I have to wait for it.

So it's not like, you know, so fancy that I can't drink it without Sarah. Who's out of town right now. Alexandra is here from Tblisi.

Hi Alexandra. And everyone else. Who those who don't know, we're drinking champagne tonight cuz we're celebrating!

It's a champagne dinner. We are celebrating that Johnson&Johnson has just relinquished all claims of any secondary patents on the tuberculosis drug, bedaquiline. Which is huge newssssss!

It's just incredible. So yeah just really special today for me, and I know for lots of y'all. Oh man.

Very unexpected, totally out of left field for me. I had no forewarning of this. I just woke up to like 50 text messages and links to this announcement, and people being like "Is this what I think it is?" Initially seemed impossible that it could be so good.

But it's good so. So many people worked on this. There's a great podcast called An Arm And A Leg, that talks about this.

It's a two-episode podcast. It's got an interview with me, but also an interview with an IT lawyer who , 20 years ago, fought the fight to get the exemptions into India's patent law that ended up being used to make this happen. It just gets at the fact that these things appear to happen all at once, but they always rely upon the work of generations of people.

And without Nandita and Phumeza suing the Indian government, convincing the Indian court that the secondary patents on bedaquiline weren't innovative and important enough to receive patent protection, none of this would have happened. So there's an interview with Phumeza too. Podcast is called An Arm And A Leg.

I think it's the best version of the story that I've encountered, so yeah. Go check it out. They updated, I think they released their episode like two days ago.

So they don't have what happened today. But yeah I was just completely taken by surprise, I had no idea. I mean, I know there was increasing pressure like Ukraine-- the Ukrainian government had made a kind of direct plea, which is unusual, and the South African government was opening an investigation.

You know, so it was looking like the number of people who were saying, Look it's just not acceptable to make a deal where some countries can get generics but some countries can't. That pressure was building, but I had no idea that they would completely walk away from their secondary patents of bedaquiline. It's a big day, and I'm really grateful to Johnson&Johnson.

Obviously you don't announce news that you're proud of on a Saturday morning at 5am or whatever, but they should be proud, is the truth. Maybe they see it as caving to pressure, or maybe they see it as bad for their shareholders, but I don't think it's either. I think it's really good news.

I think it's really good news for the company, I think it's really good news for the world, and I basically think that when companies do things that are good, they tend to work out. I know that's not a particularly capitalist view that I take, but it's been my experience, you know. You create a lot of value, then you are gonna capture enough of it to be fine.

That's the Hank Green motto that I've taken to heart. Anyway, it's really really exciting. It's a real Pizzamas miracle.

I don't think anyone did it /for/ Pizzamas, but if they did... double cheers. Because it made me really happy during this most special time of the year. You can go to Pizzamas.com and get all the pizzamas.

Except the shirt that I'm wearing, it's from last year's Pizzamas. I'm so good at marketing. I should probably be wearing one of this year's shirts.

But maybe wearing this shirt just reminds you that hey, there are great shirts that are available ONLY during Pizzamas. And if you miss it, you miss it forever. You know?

At the same time, as UntappedInkWell always points out, I don't want to create pressure on people to buy stuff that they can't afford. So don't spend money you can't afford to spend on Pizzamas. Pizzamas is fundamentally, profoundly, deeply, a luxury.

Like on every level, it's a luxury. John, no particular reason, but do you have any thoughts on video-assisted refereeing, asks Paul. Yes.

It's fine if you use it well. But in England, they use it exceptionally poorly, which is astonishing, because England is the wealthiest football-ing nation in the world, and it has the most popular league in the world. But they do not do a good job with the VAR.

And that's ok. Because why is it ok? It's ok because football is not that important.

You know? As Jürgen Klopp said after the game, it was a great performance. Liverpool played great, and that's all you can do.

You can't control the things outside of your control. And I, I'm really trying to take that to heart. Also Wimbledon won today, so that made things a little easier; their first home win in 7 months.

That felt really good. Ali Al-Hamadi, our Iraqi superstar from Liverpool, with the Liverpudlian, with the Scouser accent. Ali Al-Hamadi scored a hat trick, which is great to see.

I love that guy. My hope for you is that some day you're able to love someone the way I love Ali Al-Hamadi. And his amazing striking for Wimbledon.

What brand of champers, John? Champers? Shampers?

It's Chandon. I think it's pretty cheap, if I'm being honest with you. It tastes-- and you can probably confirm this on the internet-- but it tastes like it costs... $26.  [Transcriber's note: John was exactly right: https://www.chandon.com/en-US/chandon-brut/1091350.html]  (smacks lips) Yeah. $26.

It's not really getting better. It might be slightly skunked. But whatever, I'm gonna drink it because it's the only bottle on the bottom row, which is the one that I'm allowed to have.

You know, I'm allowed to have any of them, but I don't want to have super fancy champagne when I'm alone and probably not gonna finish the bottle. So I'm gonna have to throw a bunch of it away. So.

It's $3? No. No.

This is more than $3. I mean, right? Andre is $3.

I've have $3 champagne. This is better than $3 champagne. Wow, I actually found one of $25.99.

Boom! See? I have a gift.

I actually do have a pretty good, like, uh.... taste for wine or whatever. I can usually taste what's expensive. Can't necessarily taste what's-- I can usually taste what's kinda good.

But I don't enjoy it enough to drink really fancy wine. (laughs) I can't believe that their website says that it's $26. That's incredible. That's pretty astonishing that I was able to do that.

There's a lot of luck involved in that, I'm not gonna lie to you. This is my library, or this is our family library. What do we have over here?

Mystery novels, mystery novels. Up there we have science fiction and fantasy. Over here we have uh sort of non-fiction, memoir-y book, memoirs, and then on the third row is some reference books that I've used, the University of Chicago Manual of Style.

Stuff like that. Which is my particular manual of style. Everyone has a different one, but I grew up working in a magazine that used the University of Chicago style manual, so I use University of Chicago style when I'm writing, it's just in my head to do so.

Charlie's here? Charlie Charlie? Hey Charlie!

Ah, Charlie, we're celebrating this evening. Hope you're well. I've caught a few of your streams recently.

You're a good streamer. I'm not surprised. You've always been great at that stuff.

Anyway, great to see you Charlie. I am really overwhelmed and grateful and nothing could bring down my mood today, you know? It's a weird thing too, cuz like nobody in my world, nobody in my regular life or world understand what this means.

So I kinda have to come here to celebrate it. You know my kids don't understand it, like why would they, they shouldn't understand, it's not.. you know. The less they know about pharmaceutical company systems at their age, the better.

So it's really nice to-- I wanted to make that video because I wanted a chance to celebrate with Nerdfigheria, and also for people in Nerdfighteria to be able to feel the um, feel it. Feel what I got to feel this morning. You know because there are people who have been working on this for 20 years who are texting me this morning just completely overwhelmed.

Christophe Perrin at Doctors Without Borders, who's a pharmacist and just an amazing person, he really is the person who helped me understand this. Like he explained to me that the secondary patent is like a pen cap that you add to a pen. Which I used in the video.

And lots of other imagery that helped me understand, like, what the kinda business strategy is, and why it's so flawed, I guess. Um, yeah. So.

Yeah it's just really-- you know there's a lot of bad news in the world and a lot of bad news all the time, and bad things happening all the time. And we all go through hard days, and it's really nice. I think it's really nice and important to celebrate when you do have those wins, whether small or big or personal or group-oriented or whatever, I just think it's really important to celebrate.

It's something I learned a really long time ago, that like if you don't stop and celebrate good moments and connection, and moments of -- you feel good, then you end up not paying enough attention to them. You end up not giving them enough of yourself, if that makes sense. So I really want to do that, and that's what I'm doing now.

Just gonna pour myself a little more Chandon. It is tasting a little bit better. I think my taste buds are getting slightly fried.

Does a glass of red wine with my mac and cheese make it appropriate for the pizza party? That's absolutely appropriate for the pizza party. It's my tenth year as a nerdfighter, I'm so glad I chose to invest in this community all those years ago.

Same, I mean, I think that's a big part of it. You know there are lots of people who are new to the community, especially right now, I think Hank's illness and a few other factors have brought a lot of people into Nerdfighteria, which is wonderful, and those people benefit a lot from the kind of like collective and collected knowledge and.. of nerdfighters who've been around for al ong time. Because that's how we learn what our shared values are you know?

You are pushing and pulling me, I'm pushing and pulling you. But hundreds of thousands of us are pushing and pulling each other, and like that's how we slowly center over a set of values and concerns and considerations, and so it's really the fact that people have invested a lot of trust and time into us that makes this work. But hopefully it's also been rewarding for you.

It's certainly been rewarding for me. Yeah. Oh boy yeah.

So. Cool day. My kids are here.

Got a sleepover happening. So I'm not gonna be able to hang out that long. Plus there's a, uh, I don't like this about myself, but there's a fight tonight, y'all.

And as the former boxing reviewer from Booklist magazine, where are the boxing books up there? Ah, they're on the... right up there. Right?

Yeah. Same row as A Brief History of 7 Killings but over that way. I'm not good at spacial-- I don't have spatial intelligence.

But anyway. I'm probably gonna watch the fight tonight, which I feel bad about. There's nothing to recommend (laughs) there's nothing to recommend boxing.

But as a long time boxing reviewer for Booklist magazine, I do feel I have some kind of like uh.. I don't know. I just like it.

Whatever. I can't defend it. There's a lot of things I like that I can't defend, come to think of it.

There's a lot of things that I do that I can't defend, you know we all contain multitudes. Oh, you know what I've been wanting to-- you know what I'm really excited about right now? I'm really excited about Walter Dean Myers.

This is not a new book by any means. And Walter Dean Myers passed away a few years ago. But I'd never read it before.

It's a children's book, like a lot of my favorite non-fiction books, especially when I'm learning about something initially. Like when I was learning about tuberculosis, I got a children's book about tuberculosis, and I was like This is so helpful.  Like this is actually answering my questions. As opposed to the books for grownups that are much more like detailed and kinda further along in their understanding, and they presume that you know x, y, and z, but I didn't know x, y, and z.

So reading a children's book can be a really helpful way of introducing yourself to a topic. And Walter Dean Myers is one of our best um, all-time best children's book writers in the history of the United States. He wrote Fallen Angels and Monster, which I believe won the first Prince award.

And he's just the best. So anyway, Walter Dean Myers wrote this biography of Toussaint L'Ouverture, and the paintings are by Jacob Lawrence, who's one of my favorite artists. And I don't have the uh, I think it's safe to say I don't have the resources just to acquire a lot of Jacob Lawrence's artwork, but like look at these.

This is Toussaint L'Ouverture being born, um, this is Toussaint L'Ouverture experiencing violence related to enslavement. There's one that I really love of the French coming to Haiti. Yeah I mean look, this is L'Ouverture's arrest.

I just love these paintings. I love-- they're so evocative. And beautiful and heartbreaking.

I wanna show you my favorite one, though. I want to show you my favorite one. Oh, it's small.

But you can see bigger versions of it elsewhere. It's the French ships like attempting to get to the shores of Haiti. Anyway, I've been thinking about this because of course, Partners In Health was founded in Haiti, the organization that we support through-- and that's helping to strengthen the healthcare system in Sierra Leone, PIH was founded in Haiti, and Haiti's had such a difficult -- is going through such a difficult period.

A friend recently described it to me as "the worst situation that Haiti's been through in 40 years" which is really saying something, given the horrors of the 2010 earthquake, the general instability periods of horrific military dictatorship, and as Paul Farmer explores in his not-children's book, The Uses Of Haiti, this is the direct result of the impoverishment of Haiti that was a direct result of the success of the slave revolt. That people in Europe and the United States, white people, saw Haiti as a massive, massive threat to the world structure. And as a result, impoverished Haiti for centuries profoundly, and I think we're still living with the aftermath of that.

You can see it in the difference between Dominican Republic and the Haitian Republic, you know? These are very different countries that share an island. One is a middle income country and the other is the move impoverished country in the Western Hemisphere.

I've just been thinking a lot about it because the folks who work at Mirebalais Hospital in Haiti are just in a terrible, terrible, terribly difficult situation. A gang recently invaded the hospital and fired shots inside of it, which is terrifying. I don't think anyone was hurt in the hospital, but many patients you know, fled, including critically ill patients, patients with infectious diseases that were in long-term treatment.

You know. Just a reminder that we don't live -- none of our systems live separately from any of our other systems. You know?

Our transportation system and medical systems and our systems of governance and systems of law enforcement and everything else are all deeply, deeply intertwined and interconnected. So I've been thinking about Toussaint L'Ouverture and Jacob Lawrence a lot. In such a time of celebration, I'm also conscious of how much suffering there is in Haiti right now.

Can I show you another thing? This is one of my mom's paintings of ginkgo leaves. Ever since I made an Anthropocene Reviewed episode about ginkgo leaves that I think is in the paperback, my mom's painted them, and I just love her paintings of ginkgo leaves so much, and we both get to love the same ginkgo tree in Indianapoliis that Kurt Vonnegut's mom used to look at when she did the dishes in the 1920's.

Or cooked food, or did whatever you did in a kitchen in the 1920's. But yeah I really love my mom's paintings. And this one in particular with gold leaf and everything.

It's just really beautiful. Painted directly onto that wood. Which is also something I like.

Oh and there's this artwork. I dunno if you've ever seen this before. It's better without the... it's better when you don't have the light on it.

Let's see if we can-- not really. How about there? It's starting to get what it's like.

So do you know what that is? Do you know what that is? I'll give a point to the first person that guesses.

It's purples. That's right, it is purples. But do you know how the artist made the purples?

It's not about tuberculosis, unfortunately. The artist made the purples-- is that TV in the corner a DFW reference? No, not consciously.

The artist made the purples because that is a photograph of what an Xbox connect sees. So an Xbox connect. the old Xbox Connect would shoot all these beams of light. That's how it would determine if you were moving and where shadows were.

And this is an artwork--a photograph of what an Xbox Connect sees when it looks at the artist, whose name is Assaf Evron. When they looked at Assaf Evron's gallery, there were these rolled up papers, these rolled up sheets of paper, rolls of paper, whatever. And the shadows cast by them is what the Xbox can't see.

But it ends up looking to me like almost like uh some kind of castle in a fantasy land, or some kind of smokestack or something. But yeah it's just what an Xbox Connect sees. And I like the idea that we ... you know, trying to find ways to concrete-ize how machines look at us.

In addition to how we look at them. So yeah. It's one of my favorite works of art in our house.

And Assaf Evron is also a really cool guy. Really interesting person. I think he's based in Chicago.

Yeah. Charlie says, "I met the guy who made the Connect at E3. Way back when.

It was a very dark room. And he was wearing sunglasses the whole demo." I you know, I uh, I've made a decision about people who wear sunglasses in dark rooms. I've made a decision and I assume that there is a medical reason why they're doing it.

Because I've worn sunglasses in dark rooms. And I don't see another reason. Unless you just really look cool in sunglasses I guess.

But That's the kind of personal decision I've made. Charlie, I just got a text from Rosianna. so that's cool. Uh, what else did I wanna show you?

Oh look at this! This is a book that the crew of Paper Towns made when we wrapped the movie. Makes me so happy.

There's Radar's Justice Smiths graffiti on the back of this. But yeah. So many great friends, so many good memories.

That was a really special experience. You know, I've been ridiculously lucky in my career of course, but I think the greatest good fortune has been to work with such cool people. You know I've definitely worked with some people who weren't cool too, I've definitely has some negative experiences, professionally of course, but I've been able to work with really lovely, deeply sincere, hard working, art-driven people over the years.

And I get very defensive sometimes, when people criticize them. Like, I can't, I just feel like a paternal rage. Cuz you know, almost everyone I've ever worked with is super nice.

And a really good person. How do I know Prof? Well, I don't know Prof.

I just know Prof's music. I listen to a lot of-- I have really good taste in music. Not to brag.

But I listen to a lot of hip hop music. So uh yeah. That's how I know Prof.

Because Prof's a pretty prominent hip hop artist, in some circles. So that's my uh. Yeah.

And Actually I think Prof's new album, what's it called, Horse? Is one of the best rap albums I've heard in years. I think it's actually really underrated.

Because kinda has like a reputation for being like a jokester prankster kinda guy, and he is, but in this album, he starts to really have deep meditations on everything from the sort of you know, universal radicalization of post-COVID, the hyper-polarization not like we're post-COVID, but mid-COVID, the hyper-polarization that has accompanied the rise of social media, and then this like you know, super disruptive, disorienting, tragic pandemic. And also he writes so well about um, I think he writes really well about race and class, and the complexities of them. So there are a couple songs on that album about how he grew up, how he was raised that are really, that are almost tough listens.

He has a reputation for being hilarious, but some of those songs are really cut-to-the-bone. I really like that album. I'm confused why it isn't listed by lots of people as one of the best 5 rap albums of the last year.

Please drop the playlist. No way. (laughs) That's private. Plus you don't want to listen to East German rap from 1987.

Like that's not... no. Um, I'll tell you artists I like. I like Prof, I like Snow Tha Product a lot, Snow Tha Product is also a YouTuber.

And she raps in both English and Spanish. I like her music and flow a lot. But I also like really popular artists.

I like Cardi B. I think Cardi B's kind of a genius, actually. I like Jay Z.

I think Jay Z is a really good rapper. Yeah. I like a wide variety of music, but I do tend to listen to a lot of hip hop.

Um. So am I drinking champagne? Yes, thank you for asking so I can tell you why.

Today the pharmaceutical company Johnson&Johnson abandoned all of its secondary patents for bedaquiline in low and middle income countries. 134 countries worldwide, every single one of them. From Brazil to India to South Africa to Ukraine. All of them.

Which means the price of this life-saving TB drug is going to drop by at least 50%. Maybe as much as 70% in the next few months. Which, in turn, will mean that twice as many people or maybe three times as many people will be able to access this medication.

Because the big buyers, whether that's governments, ministries of health, in countries like Brazil or Indonesia, or whether it's organizations like the Global Fund or Partners In Health. I mean the price of bedaquiline is gonna go down so much. And it's really, really important as a drug.

It's important on a bunch of levels. It's emerging in importance in terms of preventative therapy as well, making sure that people-- so if you really wanted to get rid of tuberculosis, which is the world's deadliest infectious disease, it kills 1.6M people a year-- if you really wanted to get rid of tuberculosis, this is what you would do. This is what we did do, actually.

When we got rid of tuberculosis. Let's say, like, uh, Dr. Salmaan Keshavjee has this great presentation about how we got rid of tuberculosis in Alaska in the 1940's and 50's.

And we didn't obviously get rid of tuberculosis completely, you can never get rid of it completely because it has animal reservoirs, it's not like smallpox, it's not like polio, TB has been with us since before modern humans existed. Like hominids before us had tuberculosis. So we're not gonna get rid of it entirely.

But we don't need to get rid of it entirely, what we need is for it not to kill 1.6M people per year. Could reduce TB deaths by 99% and it would still be a tragedy, you know, it would kill 16,000 people per year, but it would be 99% better than it is now. So what we did in Alaska is really search, treat, and prevent.

So we did really aggressive case finding. Any time anyone came in to a clinic with a cough, with night sweats, with any symptoms that resembled TB, with spinal deformation, you know that could be associated with TB that's invaded the spinal cord, any of that stuff. They would test for TB, and if they found a case, they would isolate the case, which is less important now, I mean you have to isolate for a hot minute, but it's less important than it used to be, because now if you're on treatment for just a week or two, the amount of bacteria that you're shedding becomes so low that it becomes very difficult for you to transmit the disease.

So that's how-- so we would isolate the cases, then we would treat the case, no matter what, which we're not doing right now, and we're not anywhere near doing it, I think eight out of nine people who need bedaquiline still don't get it. And then we would also prevent cases by offering some kind of preventative therapy, which at the time was quite complicated, but now is easier. Now it's still complicated, I'll get to that, we'd offer preventative therapy to all their close contacts, let's say you live in a home like mine.

You live in a home, you've got two kids and a spouse, and I test positive for TB. Ok well then my kids and my spouse need to get preventative therapy. Which now is one month of antibiotics.

Now, is it hard to convince -- look, it would be hard -- it's hard to convince people to take a month of antibiotics when they aren't sick. Like that's a hard thing to do. Because you know, yes it will ensure you don't get tuberculosis, but there's a good chance you won't get tuberculosis anyway and like, it's a difficult thing.

Like look, lots of people don't finish their 5-day courses of antibiotics for strep throat, right? so like of course it's difficult to take antibiotics for a month. There's all kinds of barriers. I don't want to pretend that it's easy, but that's kind of what you would do.

You would be really aggressive about case finding, you'd be really aggressive about treating every single person who you identify as having active tuberculosis disease, and then you would offer preventative therapy to kind of like a ring of people around them. The people in their household. If you did that, pretty quickly, you start to dramatically reduce the burden of tuberculosis.

We saw it in Alaska, we saw it in the continental United States ten years earlier, we saw it in Sweden and Germany and France and Australia, in Japan, in South Korea, we've seen it over and over again. So we know exactly what to do. It's just that it's expensive.

Now, it's less expensive than it's ever been. Right? Because we have cheaper TB tests that are more accurate than we've ever had before.

And we have -- and the price of the medicine has just dropped by at least 50%, maybe more. Or the price of one of the three medicines. And another one of the three medicines is pretty cheap.

And the third one is a problem. But we don't have to talk about that right now. So that's what you would do.

And you could do that. For a few hundred million dollars, you could do it in several different countries at the same time, and prove that it's doable. So then the world would stop saying what they currently say, which is that TB is complicated and that's why we haven't solved it.

Well it's not that complicated, because we have solved it, right? Like, we have solved it in much of the world. That's -- there's sort of two worlds now.

There's the world that worries about TB and the world that doesn't. And those aren't strictly geographical worlds. Like United States is going to have 4 or 5,000 cases of tuberculosis this year, of active cases of tuberculosis.

Every time a new story drops that somebody has active TB in the United States, a bunch of people email me. And I'm like, no like, you know, every day 30 people get diagnosed with active TB in the United States. It's just that it's mostly people who are unhoused, people who a lot of times it's people who are refugees, people who have had latent TB infections for decades but then experience some kind of profound, either through diabetes or malnutrition, or some other profound shock to the system, the balance upsets, and the TB reactivates.

Or it's you know, people who are imprisoned, commonly, because they're in really confined environments where the ventilation is poor. So it's not just like a rich country- poor country problem. And anyone can get TB, you get TB, I mean anyone can get tuberculosis.

You get... you know, it's an airborne thing. Like you can get it on a bus in New York City. You can get it anywhere.

But you're much more likely to get active disease if you are marginalized or if you are ina really crowded living condition, or if you're malnourished or if you have diabetes or if you have other like kind of like co-infections. HIV especially. So there are these two worlds.

There is the world that doesn't worry about tuberculosis, and then there's the world that worries so much about tuberculosis that it's the most stigmatized disease on earth. Like people who get TB are often dropped off at a tuberculosis hospital and never hear from their families again. Because it's such a source of shame, embarrassment, horror, to have someone with -- experience that in your family.

So we have to understand that we can do this, and we know we can do this because we have done it.  It's just that we have to re-imagine the world that-- we have to re-imagine that all human lives are equally valuable. And we have to imagine how to redistribute resources if all human lives were equally valuable. If we valued human lives equally, how would we distribute public resources?

Well obviously we would cure tuberculosis quite quickly. right? So I think that like, alongside these intermediate wins, the big argument that we're trying to make is that nobody should be dying of TB in 2023, and the fact that people are is a result of human-built systems, and that has a human-based solution. Which is terrible, terrifying, awful to think, but also kind of encouraging.

Because we know the solution. Like, we are the solution. So yeah.

So that's why I'm celebrating. That was a long answer to your question. Path says, "My mom -- my nan lost a lung to TB." Very common, unfortunately.

Still common. Um, and that's the other thing, you know? If we identify-- your nan might have gotten TB before we had good treatments, but like, but if we identified TB earlier in patients, we could spare so much suffering.

All the surgeries and expense, the times they have to get lobes of their lungs removed, we could deal with all of that just with earlier diagnosis and treatment. So I am -- look, I've never been more hopeful about this. But it's also it's really hard, it's complicated, it's multi-factoral, it's all that stuff that real life is.

So yeah. We are now, but we are now entering-- I hope-- we're working toward a better shared world, and a world that values lives more appropriately. But we have a long way to go of course and uh, lots of frustrations along the way.

But on the days when you have a win, you have a win. So I'm celebrating today.  I realize I haven't talked at all about Pizzamas. But uh, Pizzamas is happening.

I'll just thank some people who recently bought something at Pizzamas. Real quick, before I have to go. It is, after all, 8:40.

Which is well past my bedtime. Oh no, like yeah. Sales have hardly gone up this entire livestream.

So I did not do a good job. Yesterday I did a great job of promoting Pizzamas. But thanks to-- (stumbles) Aristatelis!

Aristatelis is maybe my favorite name ever. (phone rings) Oh, that's my wife. I'm gonna answer. (picks up facetime) I'm doing a livestream. Hi.  Sarah (on the phone): Oh, hi! 

John: You wanna be in it? 

S: sure! 

J: It's Sarah, everybody. 

S: Hey everybody! 

J: We're celebrating because of the J&J thing.

S: Yay! 

J: Don't worry, I've only drinken $26 champagne, none of the fancy stuff.

S: (laughs) That's fine, you deserve any, we can get some more. But I'll let you go, I was just gonna say hello. We're in (indistinguishable)(?~38:12). 

J: Ok great. 

S: I'll catch you later.

J: Why don't you call Alice, I'm sure she'd love to talk to you

S: Ok! I will

J: Alright. Bye. 

S: Bye

J: Alright. Um, Aristatelis! What a great name. Michael.

Ivory. David. Lauren.

Amy, Eric Lana, or Lana, and Mackayla, all have ordered stuff at Pizzamas.com. Let's just-- let's look at what Lana got. Lana, who's Canadian, got the neon sign!

Ah, I gave my daughter the neon sign this year, and she's so excited about it. She just set it up in her bedroom, and uh, also got the Pizza John Eras Tour shirt. Which is probably in my top 5 all-time pizzamas shirts.

I love it so much. Yeah. So.

That's um, that's the news! That's the news. And then uh, just now, just in the last few seconds, Natasha and Angel and Kevin and uh, Cameron and Darby all ordered stuff from Pizzamas.com.

Kevin got the Pizza John blanket, and the Pizza John hot sauce. So thank you Kevin. Thanks to everyone who's ordered through Pizzamas, it is gonna be I think the best Pizzamas ever.

Which is very exciting, and uh, really just kind of incredulous that after so many years into a ridiculous holiday, I've started to have a relationship with the holiday that's unironic. You know? It started out as a bit, and now it's still a bit, but it's a bit with some teeth. (laughs) Like, i'm like, I'm excited for Pizzamas.

Hank texted me earlier today and he was like Pizzamas is so great. And I was like, I know. It's great!

It's so nice of Johnson&Johnson to schedule their big announcement for the Saturday at 5am of Pizzamas. (laughs) So thank you all for everything. Thanks for being here with me. Six consecutive nights of live-streaming.

It's been a blast. And I hope to see you tomorrow. It's gonna get a little more complicated for me here at the end of Pizzamas, especially since I'm going to -- travelling internationally, but I believe in myself.

So we'll figure it out. So thank y'all again, DFTBA, and I will see you.... tomorrow.